GGCX

Across TCGA patient cohorts, GGCX RNA expression is significantly associated with the protein abundance of many other proteins, with 13,588 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GGCX-associated proteins across cancer lineages are XPO1, YTHDC1, and ZNF638. Each is linked with GGCX in more than 3 cancer types. Because this analysis shows association rather than direction, both GGCX-to-partner and partner-to-GGCX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGCX versus XPO1 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GGCX→partner) and Y-score (partner→GGCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	XPO1 →	+0.268	+0.549	<.001	.005	3	4
HNSC	YTHDC1 →	+0.255	+0.460	<.001	.008	3	4
HNSC	ZNF638 →	+0.314	+0.541	<.001	.005	3	4
HNSC	CAD →	+0.331	+0.456	<.001	.001	3	4
LSCC	KDM3A →	+0.461	+0.303	<.001	<.001	3	4
LSCC	SRRT →	+0.164	+0.238	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,588 associations by consensus.

GGCX vs XPO1 — HNSC

Explore this scatter interactively →