GGACT

Across TCGA cell cohorts, GGACT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GGACT-associated GO terms across cancer lineages are Protein demannosylation, Protein alpha-1,2-demannosylation, and Regulation of endoplasmic reticulum unfolded protein response. Each is linked with GGACT in more than 8 cancer types. Because this analysis shows association rather than direction, both GGACT-to-partner and partner-to-GGACT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein demannosylation grouped by GGACT-low versus GGACT-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGACT→partner) and Y-score (partner→GGACT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein demannosylation →	+0.074	+0.865	<.001	<.001	3	9
LARGE_INTESTINE	Protein alpha-1,2-demannosylation →	+0.074	+0.865	<.001	<.001	3	9
BREAST	Regulation of endoplasmic reticulum unfolded protein response →	+0.065	+0.888	<.001	.001	3	8
URINARY_TRACT	Meiotic chromosome segregation →	-0.117	-1.039	<.001	<.001	3	8
LUNG_SCLC	Sperm motility →	-0.096	-1.103	<.001	.005	3	8
LUNG_SCLC	Flagellated sperm motility →	-0.096	-1.103	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Protein demannosylation by GGACT expression — LARGE_INTESTINE

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