GGA3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GGA3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,304 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GGA3-associated genes across cancer lineages are HNRNPA0, C11orf95, and RBFOX2. Each is linked with GGA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both GGA3-to-partner and partner-to-GGA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGA3 versus HNRNPA0 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGA3→partner) and Y-score (partner→GGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHNRNPA0 →-0.434-0.209<.001.00336
CCRCCC11orf95 →-0.588-0.098<.001.00735
LSCCRBFOX2 →-0.484-0.199<.001<.00135
LSCCPIAS3 →-0.606-0.150<.001<.00135
HNSCSMARCC1 →-0.435-0.261<.001<.00135
HNSCGLI2 →-0.928-0.164<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,304 associations by consensus.

GGA3 vs HNRNPA0 — UCEC

Per-sample scatter of GGA3 vs HNRNPA0 in UCEC (Pearson r = -0.36).

Explore this scatter interactively →

Exploration