GGA1

Across TCGA patient cohorts, GGA1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,345 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GGA1-associated genes across cancer lineages are GCAT, PICK1, and DDX17. Each is linked with GGA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GGA1-to-partner and partner-to-GGA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGA1 versus GCAT in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGA1→partner) and Y-score (partner→GGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GCAT →	+1.003	+1.004	<.001	<.001	3	5
BRCA	PICK1 →	+0.541	+0.254	<.001	<.001	3	5
BRCA	DDX17 →	+0.638	+0.216	<.001	<.001	3	4
BRCA	POLDIP3 →	+0.383	+0.190	<.001	<.001	3	4
GBM	PPP6R2 →	+0.473	+0.345	<.001	<.001	3	4
BRCA	HMGXB4 →	+0.639	+0.257	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,345 associations by consensus.

GGA1 vs GCAT — OV

Explore this scatter interactively →