GGA1

Across TCGA cell cohorts, GGA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,639 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GGA1-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of T-helper 17 cell lineage commitment, and Microtubule nucleation. Each is linked with GGA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both GGA1-to-partner and partner-to-GGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by GGA1-low versus GGA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGA1→partner) and Y-score (partner→GGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.169	+0.987	<.001	<.001	3	17
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.253	+0.870	.001	<.001	3	16
BONE	Microtubule nucleation →	+0.166	+1.110	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.109	-1.003	<.001	<.001	3	15
KIDNEY	Negative regulation of brown fat cell differentiation →	+0.171	+0.996	.008	.004	3	15
BONE	Subtelomeric heterochromatin formation →	+0.145	+0.976	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,639 associations by consensus.

Negative regulation of chromosome condensation by GGA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →