GFUS

Across TCGA patient cohorts, GFUS RNA expression is significantly associated with the protein abundance of many other proteins, with 7,774 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GFUS-associated proteins across cancer lineages are HGH1, FBXL6, and GART. Each is linked with GFUS in more than 6 cancer types. Because this analysis shows association rather than direction, both GFUS-to-partner and partner-to-GFUS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFUS versus HGH1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GFUS→partner) and Y-score (partner→GFUS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HGH1 →	+0.375	+0.798	<.001	.001	3	7
OV	FBXL6 →	+0.593	+0.830	<.001	<.001	3	5
HNSC	GART →	+0.282	+0.874	<.001	<.001	3	5
OV	SCRIB →	+0.352	+0.618	<.001	<.001	3	5
OV	MROH1 →	+0.395	+0.730	.003	<.001	3	4
OV	NAPRT →	+0.754	+1.017	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,774 associations by consensus.

GFUS vs HGH1 — OV

Explore this scatter interactively →