GFUS

Across TCGA cell cohorts, GFUS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,316 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GFUS-associated GO terms across cancer lineages are Endosome to plasma membrane protein transport, miRNA-mediated gene silencing by mRNA destabilization, and Spermidine transmembrane transport. Each is linked with GFUS in more than 9 cancer types. Because this analysis shows association rather than direction, both GFUS-to-partner and partner-to-GFUS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome to plasma membrane protein transport grouped by GFUS-low versus GFUS-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFUS→partner) and Y-score (partner→GFUS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Endosome to plasma membrane protein transport →	+0.145	+0.975	<.001	<.001	3	10
OVARY	miRNA-mediated gene silencing by mRNA destabilization →	+0.127	+0.853	<.001	<.001	3	10
BREAST	Spermidine transmembrane transport →	+1.191	+1.123	<.001	<.001	3	9
STOMACH	Mitochondrial potassium ion transmembrane transport →	+0.121	+1.063	.006	.003	2	10
BLOOD_Leukemia	Negative regulation of interleukin-4 production →	-0.284	-0.637	.002	.001	3	9
LUNG_NSCLC_LUAD	Disaccharide transport →	+1.020	+1.070	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,316 associations by consensus.

Endosome to plasma membrane protein transport by GFUS expression — BLOOD_Lymphoma

Explore this box plot interactively →