GFRA3

Across TCGA patient cohorts, GFRA3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,549 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GFRA3-associated genes across cancer lineages are RPS27AP18, GDF11, and FNDC5. Each is linked with GFRA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GFRA3-to-partner and partner-to-GFRA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFRA3 versus RPS27AP18 in UCEC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA3→partner) and Y-score (partner→GFRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS27AP18 →	+0.761	+1.025	<.001	<.001	3	3
UCEC	GDF11 →	+0.903	+0.890	.001	.001	3	2
LUAD	FNDC5 →	+0.490	+0.844	.006	<.001	3	2
PDAC	NDUFB4P1 →	-0.507	-0.513	.002	.004	3	2
LUAD	DLL3 →	+1.396	+1.063	<.001	<.001	3	2
LUAD	TUBB2B →	+1.795	+1.128	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,549 associations by consensus.

GFRA3 vs RPS27AP18 — UCEC

Explore this scatter interactively →