GFRA3

Across TCGA patient cohorts, GFRA3 mutation is significantly associated with the RNA expression of many other genes, with 579 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFRA3-associated genes across cancer lineages are RN7SL782P, RNU1-153P, and CYTH1P1. Each is linked with GFRA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GFRA3-to-partner and partner-to-GFRA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL782P grouped by GFRA3-low versus GFRA3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA3→partner) and Y-score (partner→GFRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL782P →	+0.240	+5.748	<.001	.001	3	3
UCEC	RNU1-153P →	-1.028	-3.807	<.001	<.001	3	2
CESC	CYTH1P1 →	+0.072	+3.608	<.001	.004	3	2
CESC	RN7SL828P →	+0.064	+4.144	<.001	.009	3	2
LUAD	RNA5SP358 →	+0.357	+4.399	<.001	.008	3	2
CESC	OR10A3 →	+0.380	+3.805	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 579 associations by consensus.

RN7SL782P by GFRA3 expression — LUAD

Explore this box plot interactively →