GFRA2

Across TCGA patient cohorts, GFRA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,404 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GFRA2-associated proteins across cancer lineages are SYNPO2_T755, KANK2, and SYNPO. Each is linked with GFRA2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GFRA2-to-partner and partner-to-GFRA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFRA2 versus SYNPO2_T755 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA2→partner) and Y-score (partner→GFRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SYNPO2_T755 →	+0.757	+0.629	.006	.002	3	9
UCEC	KANK2 →	+0.771	+0.669	<.001	<.001	3	8
CCRCC	SYNPO →	+0.438	+0.528	<.001	<.001	3	8
HNSC	SYNPO2 →	+0.646	+0.524	<.001	<.001	3	8
HNSC	F13A1 →	+0.574	+0.676	<.001	<.001	3	8
UCEC	TNS2 →	+0.351	+0.662	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,404 associations by consensus.

GFRA2 vs SYNPO2_T755 — UCEC

Explore this scatter interactively →