GFRA2

Across TCGA patient cohorts, GFRA2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,584 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GFRA2-associated genes across cancer lineages are DPY19L2P5, SNAP25, and RTN1. Each is linked with GFRA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GFRA2-to-partner and partner-to-GFRA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFRA2 versus DPY19L2P5 in OV, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA2→partner) and Y-score (partner→GFRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPY19L2P5 →	+0.520	+2.388	.001	.008	3	2
GBM	SNAP25 →	+1.827	+0.788	<.001	<.001	3	2
GBM	RTN1 →	+1.214	+0.826	<.001	<.001	3	2
LSCC	AXIN2 →	+1.686	+1.461	.005	.006	3	2
LSCC	GRID1 →	+0.708	+1.131	.001	.007	3	2
LSCC	COPS8P2 →	+0.664	+1.802	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,584 associations by consensus.

GFRA2 vs DPY19L2P5 — OV

Explore this scatter interactively →