GFRA1

Across TCGA patient cohorts, GFRA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,050 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GFRA1-associated proteins across cancer lineages are PPP1R12B, RPS2, and SEPTIN4. Each is linked with GFRA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GFRA1-to-partner and partner-to-GFRA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFRA1 versus PPP1R12B in UCEC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA1→partner) and Y-score (partner→GFRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R12B →	+1.447	+0.858	<.001	<.001	3	8
BRCA	RPS2 →	-0.246	-2.314	<.001	<.001	3	8
GBM	SEPTIN4 →	+0.535	+1.091	<.001	<.001	3	8
OV	CNRIP1 →	+0.691	+1.100	<.001	<.001	3	8
COAD	AKAP12 →	+0.919	+0.786	<.001	<.001	3	8
GBM	HSPA12A →	+0.707	+1.080	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,050 associations by consensus.

GFRA1 vs PPP1R12B — UCEC

Explore this scatter interactively →