GFRA1

Across TCGA cell cohorts, GFRA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,833 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GFRA1-associated GO terms across cancer lineages are Cell division, Golgi vesicle transport, and Regulation of protein localization to Cajal body. Each is linked with GFRA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GFRA1-to-partner and partner-to-GFRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by GFRA1-low versus GFRA1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFRA1→partner) and Y-score (partner→GFRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cell division →	+0.075	+1.468	<.001	<.001	3	10
SKIN	Golgi vesicle transport →	+0.063	+1.825	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of protein localization to Cajal body →	+0.042	+0.084	<.001	.002	3	8
LARGE_INTESTINE	Positive regulation of protein localization to Cajal body →	+0.042	+0.084	<.001	.002	3	8
SKIN	Regulation of syncytium formation by plasma membrane fusion →	+0.106	+1.838	<.001	<.001	3	8
SKIN	Regulation of translational initiation →	+0.072	+1.567	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,833 associations by consensus.

Cell division by GFRA1 expression — SKIN

Explore this box plot interactively →