GFM2

Across TCGA cell cohorts, GFM2 mutation is significantly associated with the mutation status of many other genes, with 1,878 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GFM2-associated genes across cancer lineages are ZDHHC14, WDR24, and DACT2. Each is linked with GFM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GFM2-to-partner and partner-to-GFM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZDHHC14 grouped by GFM2-low versus GFM2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM2→partner) and Y-score (partner→GFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZDHHC14 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Leukemia	WDR24 →	+3.845	+4.794	<.001	<.001	1	3
BLOOD_Leukemia	DACT2 →	+4.430	+3.823	.001	.001	1	3
BLOOD_Leukemia	ATAD2 →	+2.675	+3.080	.004	.004	1	3
BLOOD_Lymphoma	XKR6 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	MAP3K15 →	+4.014	+4.969	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,878 associations by consensus.

ZDHHC14 by GFM2 expression — BLOOD_Lymphoma

Explore this box plot interactively →