GFER

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GFER protein abundance is significantly associated with the RNA expression of many other genes, with 10,639 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GFER-associated genes across cancer lineages are ARHGAP9, TOM1L1, and JMJD8. Each is linked with GFER in more than 3 cancer types. Because this analysis shows association rather than direction, both GFER-to-partner and partner-to-GFER results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFER versus ARHGAP9 in UCEC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFER→partner) and Y-score (partner→GFER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECARHGAP9 →+0.746+0.257<.001.00434
OVTOM1L1 →-0.528-0.428.005.00933
BRCAJMJD8 →+0.906+0.459<.001<.00133
UCECCYTH4 →+0.735+0.227<.001<.00133
LSCCPIK3CG →+0.556+0.199.003.00233
GBMZNF286A →-0.450-0.244<.001.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,639 associations by consensus.

GFER vs ARHGAP9 — UCEC

Per-sample scatter of GFER vs ARHGAP9 in UCEC (Pearson r = 0.27).

Explore this scatter interactively →

Exploration