Across TCGA patient cohorts, GET3 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GET3-associated genes across cancer lineages are XBP1, p62 Lck ligand, and Rab25. Each is linked with GET3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GET3-to-partner and partner-to-GET3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GET3→partner) and Y-score (partner→GET3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	XBP1 →	-0.273	-3.000	<.001	.036	3	1
UCEC	p62 Lck ligand →	+0.462	+3.000	.014	.037	1	1
UCEC	Rab25 →	-0.405	-3.000	.034	.037	1	1
UCEC	Annexin-1 →	+0.953	+3.000	.001	.037	1	1
UCEC	BRCA2 →	-0.152	-2.992	.038	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

GET3 survival (RNA) · tumor vs normal (RNA) · all GET3 data types