GET1

Across TCGA patient cohorts, GET1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,872 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GET1-associated genes across cancer lineages are OSR1, KLHL35, and FCRL3. Each is linked with GET1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GET1-to-partner and partner-to-GET1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GET1 versus OSR1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GET1→partner) and Y-score (partner→GET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OSR1 →	-0.959	-0.614	.006	.004	3	2
GBM	KLHL35 →	+0.693	+0.385	<.001	.005	3	2
BRCA	FCRL3 →	-0.852	-0.547	.001	.004	3	2
UCEC	ZRANB2-AS2 →	+0.448	+0.310	.001	.008	3	2
BRCA	NKG7 →	-1.636	-0.697	.004	.001	3	2
BRCA	MRPS30 →	+1.533	+0.655	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,872 associations by consensus.

GET1 vs OSR1 — BRCA

Explore this scatter interactively →