GEMIN8P2

Across TCGA pan-cancer cohorts, GEMIN8P2 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated GEMIN8P2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher GEMIN8P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GEMIN8P2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

THCA, KICH, and DLBC are the cancer types where GEMIN8P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.673	0.961	<.001	72	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	27	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
ESCA	DFS	Tertile	All	0.240	0.804	.008	27	view →
BLCA	OS	Tertile	All	0.755	0.587	.021	24	view →
ACC	DFS	Tertile	IV	0.056	0.404	.003	18	view →
PAAD	OS	Tertile	II,III,IV	0.867	0.410	.017	15	view →
KIRC	DFS	Tertile	All	0.359	0.644	.016	12	view →
LUSC	OS	Tertile	All	0.285	0.414	.032	12	view →
LUAD	OS	Tertile	IV	0.511	0.378	.009	12	view →
SKCM	OS	Tertile	All	0.665	0.796	.024	3	view →
LGG	DFS	Tertile	All	0.616	0.751	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

GEMIN8P2–THCA (OS)

Open the THCA breakdown →