Across TCGA pan-cancer cohorts, GEMIN8P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of GEMIN8P2’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where GEMIN8P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GEMIN8P2 is over-expressed in tumor.
LUSC are the cancer types where GEMIN8P2 tumor–normal differential expression is most reproducible.