GEMIN7

Across TCGA cell cohorts, GEMIN7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,804 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GEMIN7-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, Regulation of protection from non-homologous end joining at telomere, and Negative regulation of protection from non-homologous end joining at telomere. Each is linked with GEMIN7 in more than 9 cancer types. Because this analysis shows association rather than direction, both GEMIN7-to-partner and partner-to-GEMIN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by GEMIN7-low versus GEMIN7-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN7→partner) and Y-score (partner→GEMIN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nucleolar large rRNA transcription by RNA polymerase I →	+0.096	+0.545	.002	.001	3	10
PANCREAS	Regulation of protection from non-homologous end joining at telomere →	+0.161	+0.726	<.001	<.001	3	9
PANCREAS	Negative regulation of protection from non-homologous end joining at telomere →	+0.161	+0.726	<.001	<.001	3	9
PANCREAS	Telomeric DNA-containing double minutes formation →	+0.161	+0.726	<.001	<.001	3	9
CNS	Antigen processing and presentation of peptide antigen via MHC class I →	-0.101	-0.397	<.001	<.001	3	9
BLOOD_Leukemia	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.089	+0.609	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,804 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by GEMIN7 expression — LUNG_SCLC

Explore this box plot interactively →