GEMIN7-AS1

Across TCGA pan-cancer cohorts, GEMIN7-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of GEMIN7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GEMIN7-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GEMIN7-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, KICH, and LIHC are the cancer types where GEMIN7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GEMIN7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.476	<.001	10	view →
KICH	Female	All	−0.890	<.001	8	view →
LIHC	Female	II,III,IV	+0.436	<.001	8	view →
BRCA	All	All	+0.336	<.001	6	view →
CHOL	Male	All	+1.645	<.001	5	view →
READ	All	All	+0.591	<.001	5	view →
THCA	Male	All	−0.362	.007	2	view →
STAD	All	II,III,IV	+0.359	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

GEMIN7-AS1–COAD

Open the COAD breakdown →