GDPD4

Across TCGA patient cohorts, GDPD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,101 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GDPD4-associated GO terms across cancer lineages are Protein modification by small protein removal, Establishment of protein localization to vacuole, and Cytosolic transport. Each is linked with GDPD4 in more than 25 cancer types. Because this analysis shows association rather than direction, both GDPD4-to-partner and partner-to-GDPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by GDPD4-low versus GDPD4-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD4→partner) and Y-score (partner→GDPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein modification by small protein removal →	+0.081	+0.403	<.001	<.001	3	26
ESCA	Establishment of protein localization to vacuole →	+0.077	+0.372	<.001	<.001	3	26
STAD	Cytosolic transport →	+0.064	+0.193	<.001	<.001	3	26
STAD	Protein dephosphorylation →	+0.061	+0.172	<.001	<.001	3	26
STAD	Endosomal transport →	+0.065	+0.184	<.001	<.001	3	25
STAD	Vacuole organization →	+0.064	+0.197	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,101 associations by consensus.

Protein modification by small protein removal by GDPD4 expression — ESCA

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