GDPD4

Across TCGA patient cohorts, GDPD4 mutation is significantly associated with the RNA expression of many other genes, with 3,145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDPD4-associated genes across cancer lineages are KATNBL1P5, MTND5P27, and RNA5SP155. Each is linked with GDPD4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDPD4-to-partner and partner-to-GDPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KATNBL1P5 grouped by GDPD4-low versus GDPD4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD4→partner) and Y-score (partner→GDPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KATNBL1P5 →	+0.306	+6.917	<.001	<.001	3	3
LUSC	MTND5P27 →	+0.152	+4.191	<.001	.009	3	3
SKCM	RNA5SP155 →	+0.450	+2.531	<.001	.001	3	3
UCEC	FRG1HP →	+0.623	+2.032	<.001	.001	3	2
UCEC	RNA5SP412 →	+0.729	+2.851	<.001	<.001	3	2
UCEC	DSN1 →	+0.495	+1.684	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,145 associations by consensus.

KATNBL1P5 by GDPD4 expression — COAD

Explore this box plot interactively →