GDPD4

Across TCGA cell cohorts, GDPD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 716 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDPD4-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of mRNA metabolic process, and Regulation of myoblast fusion. Each is linked with GDPD4 in more than 6 cancer types. Because this analysis shows association rather than direction, both GDPD4-to-partner and partner-to-GDPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by GDPD4-low versus GDPD4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD4→partner) and Y-score (partner→GDPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.078	+0.125	.001	.002	3	7
BREAST	Negative regulation of mRNA metabolic process →	+0.054	+0.097	.001	.003	2	7
PANCREAS	Regulation of myoblast fusion →	+0.081	+0.169	.004	.003	3	6
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.177	.001	.002	3	6
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.079	+0.124	.001	.002	3	6
PANCREAS	Positive regulation of protein localization to nucleus →	+0.083	+0.161	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 716 associations by consensus.

Negative regulation of myoblast fusion by GDPD4 expression — OVARY

Explore this box plot interactively →