GDPD4

Across TCGA cell cohorts, GDPD4 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDPD4-associated genes across cancer lineages are SIGLEC5, GPR101, and PTF1A. Each is linked with GDPD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDPD4-to-partner and partner-to-GDPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC5 grouped by GDPD4-low versus GDPD4-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD4→partner) and Y-score (partner→GDPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SIGLEC5 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	GPR101 →	+0.070	+4.906	<.001	.006	3	1
OESOPHAGUS	PTF1A →	+0.346	+4.906	<.001	.006	3	1
OESOPHAGUS	OR6X1 →	+0.020	+4.906	<.001	.006	3	1
BLOOD_Leukemia	NOL4 →	+0.881	+3.584	<.001	.004	3	1
BLOOD_Leukemia	HRG →	+0.278	+3.177	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

SIGLEC5 by GDPD4 expression — OESOPHAGUS

Explore this box plot interactively →