GDPD3

Across TCGA pan-cancer cohorts, GDPD3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GDPD3 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GDPD3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GDPD3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where GDPD3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	1.000	0.754	.001	14	view →
PDAC	OS	Tertile	All	0.654	0.446	.039	2	view →
CCRCC	DFS	Tertile	All	1.000	0.901	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GDPD3–UCEC (OS)

Open the UCEC breakdown →