GDPD3

Across TCGA cell cohorts, GDPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,699 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDPD3-associated GO terms across cancer lineages are ERBB3 signaling pathway, ERBB2-ERBB3 signaling pathway, and Positive regulation of striated muscle contraction. Each is linked with GDPD3 in more than 11 cancer types. Because this analysis shows association rather than direction, both GDPD3-to-partner and partner-to-GDPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB3 signaling pathway grouped by GDPD3-low versus GDPD3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD3→partner) and Y-score (partner→GDPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ERBB3 signaling pathway →	+0.178	+0.989	.001	.007	2	12
OVARY	ERBB2-ERBB3 signaling pathway →	+0.178	+0.989	.001	.007	2	12
BONE	Positive regulation of striated muscle contraction →	-0.239	-0.654	.004	.002	3	10
LUNG_NSCLC_LUAD	Establishment of epithelial cell apical/basal polarity →	-0.163	-1.736	<.001	<.001	3	10
OVARY	Mycotoxin metabolic process →	-0.273	-1.215	<.001	<.001	3	9
OVARY	Aflatoxin metabolic process →	-0.273	-1.215	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,699 associations by consensus.

ERBB3 signaling pathway by GDPD3 expression — OVARY

Explore this box plot interactively →