Across TCGA patient cohorts, GDI1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,291 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDI1-associated genes across cancer lineages are KLHDC1, ZNF287, and ZEB1. Each is linked with GDI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GDI1-to-partner and partner-to-GDI1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDI1→partner) and Y-score (partner→GDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KLHDC1 →	+0.889	+0.354	<.001	<.001	3	8
GBM	ZNF287 →	+0.484	+0.364	.001	<.001	3	7
COAD	ZEB1 →	+0.851	+0.255	<.001	<.001	3	7
BRCA	CST2 →	+1.611	+0.303	<.001	<.001	3	7
COAD	MSRB3 →	+1.026	+0.293	<.001	<.001	3	7
UCEC	POU6F1 →	+0.525	+0.292	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,291 associations by consensus.

Exploration

GDI1 survival (RNA) · tumor vs normal (RNA) · all GDI1 data types