GDF7

Across TCGA patient cohorts, GDF7 RNA expression is significantly associated with the RNA expression of many other genes, with 17,715 significant associations in total. THYM shows the largest number of these associations.

The most reproducible GDF7-associated genes across cancer lineages are HECTD4, NRIP2, and EPC1. Each is linked with GDF7 in more than 27 cancer types. Because this analysis shows association rather than direction, both GDF7-to-partner and partner-to-GDF7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF7 versus HECTD4 in THYM, with a Pearson correlation of 0.40.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF7→partner) and Y-score (partner→GDF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	HECTD4 →	+1.062	+0.859	<.001	<.001	3	28
THYM	NRIP2 →	+1.462	+0.751	<.001	<.001	3	28
ACC	EPC1 →	+0.663	+0.324	<.001	.002	3	28
SCLC	TSC1 →	+1.299	+0.135	.001	.004	3	27
GBM	ZNF8 →	+0.697	+0.410	<.001	<.001	3	27
UCS	BOD1L1 →	+1.002	+1.342	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,715 associations by consensus.

GDF7 vs HECTD4 — THYM

Explore this scatter interactively →