GDF7

Across TCGA patient cohorts, GDF7 protein abundance is significantly associated with the RNA expression of many other genes, with 200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDF7-associated genes across cancer lineages are CUBN, CACNG1, and PECR. Each is linked with GDF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDF7-to-partner and partner-to-GDF7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF7 versus CUBN in UCEC, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF7→partner) and Y-score (partner→GDF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CUBN →	+1.840	+0.380	.003	.007	3	1
UCEC	CACNG1 →	+0.520	+0.443	.001	.003	3	1
UCEC	PECR →	+1.096	+0.380	.003	.007	3	1
UCEC	MOCS1 →	+2.050	+0.480	.001	.004	3	1
UCEC	SDCBP2 →	+1.635	+0.480	.008	.004	3	1
UCEC	LRRN4 →	+1.859	+0.410	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 200 associations by consensus.

GDF7 vs CUBN — UCEC

Explore this scatter interactively →