GDF7

Across TCGA cell cohorts, GDF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,091 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible GDF7-associated GO terms across cancer lineages are Glycerolipid biosynthetic process, Potassium ion transmembrane transport, and Phospholipid biosynthetic process. Each is linked with GDF7 in more than 7 cancer types. Because this analysis shows association rather than direction, both GDF7-to-partner and partner-to-GDF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerolipid biosynthetic process grouped by GDF7-low versus GDF7-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF7→partner) and Y-score (partner→GDF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.051	+0.716	<.001	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Potassium ion transmembrane transport →	-0.046	-0.124	<.001	.004	3	7
URINARY_TRACT	Phospholipid biosynthetic process →	+0.047	+0.840	<.001	<.001	3	7
BLOOD_Leukemia	Mitochondrial electron transport, cytochrome c to oxygen →	+0.052	+0.050	.008	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Potassium ion transport →	-0.046	-0.124	.001	.004	3	6
LIVER	Renal vesicle formation →	+1.031	+1.164	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,091 associations by consensus.

Glycerolipid biosynthetic process by GDF7 expression — URINARY_TRACT

Explore this box plot interactively →