GDF10

Across TCGA patient cohorts, GDF10 protein abundance is significantly associated with the RNA expression of many other genes, with 6,120 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GDF10-associated genes across cancer lineages are MFNG, CHRDL1, and MEOX2. Each is linked with GDF10 in more than 3 cancer types. Because this analysis shows association rather than direction, both GDF10-to-partner and partner-to-GDF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF10 versus MFNG in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF10→partner) and Y-score (partner→GDF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MFNG →	+0.855	+1.115	<.001	.001	3	4
BRCA	CHRDL1 →	+1.851	+1.090	<.001	.001	3	4
BRCA	MEOX2 →	+1.582	+1.202	<.001	<.001	3	4
BRCA	ASPA →	+0.989	+1.550	<.001	<.001	3	4
BRCA	FHL5 →	+1.372	+1.845	<.001	<.001	3	4
HNSC	CASQ2 →	+2.115	+1.369	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,120 associations by consensus.

GDF10 vs MFNG — BRCA

Explore this scatter interactively →