GDF10

Across TCGA cell cohorts, GDF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 471 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDF10-associated GO terms across cancer lineages are Positive regulation of macrophage chemotaxis, Nucleosome assembly, and Antibody-dependent cellular cytotoxicity. Each is linked with GDF10 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDF10-to-partner and partner-to-GDF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of macrophage chemotaxis grouped by GDF10-low versus GDF10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF10→partner) and Y-score (partner→GDF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of macrophage chemotaxis →	+0.116	+0.295	.003	.008	3	3
SOFT_TISSUE	Nucleosome assembly →	+0.060	+0.468	.003	.008	3	3
BLOOD_Leukemia	Antibody-dependent cellular cytotoxicity →	-1.017	-0.775	<.001	.005	3	3
BLOOD_Leukemia	Type IIa hypersensitivity →	-1.017	-0.775	<.001	.005	3	3
BLOOD_Leukemia	Type II hypersensitivity →	-1.017	-0.775	<.001	.005	3	3
BLOOD_Leukemia	Lymphocyte chemotaxis →	-0.105	-0.752	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 471 associations by consensus.

Positive regulation of macrophage chemotaxis by GDF10 expression — SOFT_TISSUE

Explore this box plot interactively →