GDE1

Across TCGA cell cohorts, GDE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDE1-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Autophagy of mitochondrion. Each is linked with GDE1 in more than 10 cancer types. Because this analysis shows association rather than direction, both GDE1-to-partner and partner-to-GDE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by GDE1-low versus GDE1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDE1→partner) and Y-score (partner→GDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Process utilizing autophagic mechanism →	+0.061	+0.567	<.001	.004	3	11
STOMACH	Autophagy →	+0.061	+0.567	<.001	.004	3	11
LUNG_SCLC	Autophagy of mitochondrion →	+0.082	+0.910	<.001	<.001	3	11
LUNG_SCLC	Membrane fusion →	+0.059	+0.874	<.001	<.001	3	10
BLOOD_Myeloma	Phosphatidylinositol phosphate biosynthetic process →	+0.049	+0.856	<.001	.001	3	10
STOMACH	Macroautophagy →	+0.059	+0.654	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,108 associations by consensus.

Process utilizing autophagic mechanism by GDE1 expression — STOMACH

Explore this box plot interactively →