GDAP1L1

Across TCGA patient cohorts, GDAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 5,410 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDAP1L1-associated genes across cancer lineages are RNA5SP413, SORBS3, and THAP3. Each is linked with GDAP1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDAP1L1-to-partner and partner-to-GDAP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by GDAP1L1-low versus GDAP1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDAP1L1→partner) and Y-score (partner→GDAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+0.986	+1.807	<.001	<.001	3	3
SKCM	SORBS3 →	+0.744	+3.220	.001	.009	3	2
SKCM	THAP3 →	+0.516	+3.245	<.001	.008	3	2
UCEC	RNA5SP414 →	+0.434	+1.965	<.001	.001	3	2
UCEC	RNA5SP411 →	+0.956	+1.924	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.560	+2.104	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,410 associations by consensus.

RNA5SP413 by GDAP1L1 expression — UCEC

Explore this box plot interactively →