GDAP1L1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GDAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GDAP1L1-associated genes across cancer lineages are CRYGD and CCL14. Each is linked with GDAP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDAP1L1-to-partner and partner-to-GDAP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGD grouped by GDAP1L1-low versus GDAP1L1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDAP1L1→partner) and Y-score (partner→GDAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINCRYGD →+0.530+4.415<.001.00731
SKINCCL14 →+0.081+4.095.003.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CRYGD by GDAP1L1 expression — SKIN

Box plot of CRYGD in GDAP1L1-low vs GDAP1L1-high samples in SKIN.

Explore this box plot interactively →

Exploration