GCSHP2

Across TCGA patient cohorts, GCSHP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,417 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GCSHP2-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Nucleoside phosphate biosynthetic process, and Regulation of microtubule-based process. Each is linked with GCSHP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GCSHP2-to-partner and partner-to-GCSHP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by GCSHP2-low versus GCSHP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSHP2→partner) and Y-score (partner→GCSHP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of mitotic cell cycle →	+0.065	+0.272	<.001	<.001	3	12
DLBC	Nucleoside phosphate biosynthetic process →	+0.089	+0.075	<.001	.008	3	11
ESCA	Regulation of microtubule-based process →	+0.057	+0.338	<.001	<.001	3	11
STAD	Regulation of carbohydrate metabolic process →	+0.048	+0.340	<.001	<.001	3	10
ESCA	Nucleobase-containing compound transport →	+0.066	+0.307	<.001	<.001	3	10
STAD	Regulation of microtubule polymerization or depolymerization →	+0.052	+0.329	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,417 associations by consensus.

Positive regulation of mitotic cell cycle by GCSHP2 expression — ESCA

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