GCSHP2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, GCSHP2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of GCSHP2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where GCSHP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GCSHP2 is over-expressed in tumor.

LUSC are the cancer types where GCSHP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GCSHP2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCAllAll+0.015.0301view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

GCSHP2–LUSC

Tumor-vs-normal expression box plot for GCSHP2 RNA in LUSC.

Open the LUSC breakdown →

Exploration