GCSAM

Across TCGA patient cohorts, GCSAM RNA expression is significantly associated with the protein abundance of many other proteins, with 11,215 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GCSAM-associated proteins across cancer lineages are STAT6, DTX3L_S539, and RAB27B. Each is linked with GCSAM in more than 3 cancer types. Because this analysis shows association rather than direction, both GCSAM-to-partner and partner-to-GCSAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCSAM versus STAT6 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSAM→partner) and Y-score (partner→GCSAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STAT6 →	+0.365	+0.401	<.001	<.001	3	4
GBM	DTX3L_S539 →	+0.532	+0.524	<.001	<.001	3	4
BRCA	RAB27B →	+0.826	+0.749	<.001	<.001	3	3
GBM	TBC1D1 →	+0.350	+0.468	.001	<.001	3	3
LUAD	PDE5A →	+0.301	+0.495	<.001	<.001	3	3
BRCA	TNXB →	+0.593	+0.641	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,215 associations by consensus.

GCSAM vs STAT6 — GBM

Explore this scatter interactively →