GCOM1

Across TCGA patient cohorts, GCOM1 protein abundance is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GCOM1-associated genes across cancer lineages are CSF3, WNT1, and FAM83C. Each is linked with GCOM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCOM1-to-partner and partner-to-GCOM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCOM1 versus CSF3 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCOM1→partner) and Y-score (partner→GCOM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CSF3 →	+2.114	+1.305	.002	.005	3	1
HNSC	WNT1 →	-0.283	-1.843	<.001	.006	3	1
HNSC	FAM83C →	-2.275	-1.281	.002	.006	3	1
HNSC	CANX →	+0.487	+1.325	.003	.004	3	1
HNSC	RAMP2 →	+0.644	+1.334	.002	.004	3	1
HNSC	TMCO1 →	+0.604	+1.719	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

GCOM1 vs CSF3 — HNSC

Explore this scatter interactively →