GCNT4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GCNT4 mutation is significantly associated with the RNA expression of many other genes, with 2,684 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCNT4-associated genes across cancer lineages are ETFA, MIR877, and CDC37L1-DT. Each is linked with GCNT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GCNT4-to-partner and partner-to-GCNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETFA grouped by GCNT4-low versus GCNT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT4→partner) and Y-score (partner→GCNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECETFA →+0.680+2.874<.001<.00133
SKCMMIR877 →+0.197+3.776<.001.00333
UCECCDC37L1-DT →+0.471+3.922<.001<.00132
UCECIGHV2-70 →+1.355+3.008.002<.00132
COADRNU6-42P →+0.794+3.105.001.00432
COADTRDJ2 →+1.005+3.536<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,684 associations by consensus.

ETFA by GCNT4 expression — UCEC

Box plot of ETFA in GCNT4-low vs GCNT4-high samples in UCEC.

Explore this box plot interactively →

Exploration