GCDH

Across TCGA patient cohorts, GCDH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,682 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCDH-associated proteins across cancer lineages are RAVER1, ILF2, and KRI1. Each is linked with GCDH in more than 6 cancer types. Because this analysis shows association rather than direction, both GCDH-to-partner and partner-to-GCDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCDH versus RAVER1 in OV, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCDH→partner) and Y-score (partner→GCDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAVER1 →	+0.329	+0.637	<.001	<.001	3	7
OV	ILF2 →	+0.318	+0.595	<.001	<.001	3	6
GBM	KRI1 →	+0.493	+0.437	<.001	.001	3	6
OV	NACC1 →	+0.413	+0.609	<.001	.001	3	6
OV	TNPO2 →	+0.321	+0.463	<.001	<.001	3	6
GBM	RFX1 →	+0.229	+0.484	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,682 associations by consensus.

GCDH vs RAVER1 — OV

Explore this scatter interactively →