GCDH

Across TCGA cell cohorts, GCDH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,969 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GCDH-associated GO terms across cancer lineages are Regulation of protein localization to chromatin, Metaphase/anaphase transition of mitotic cell cycle, and Nucleosome disassembly. Each is linked with GCDH in more than 14 cancer types. Because this analysis shows association rather than direction, both GCDH-to-partner and partner-to-GCDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to chromatin grouped by GCDH-low versus GCDH-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCDH→partner) and Y-score (partner→GCDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of protein localization to chromatin →	+0.096	+0.949	.002	<.001	3	15
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.164	+0.801	<.001	<.001	3	14
STOMACH	Nucleosome disassembly →	+0.141	+1.032	.001	<.001	2	15
SOFT_TISSUE	Mitochondrial tRNA wobble uridine modification →	+0.157	+0.900	<.001	<.001	3	13
BONE	Metaphase/anaphase transition of cell cycle →	+0.169	+0.814	<.001	<.001	3	13
PANCREAS	DNA replication checkpoint signaling →	+0.128	+0.991	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

Regulation of protein localization to chromatin by GCDH expression — OESOPHAGUS

Explore this box plot interactively →