GCC2

Across TCGA patient cohorts, GCC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,989 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GCC2-associated proteins across cancer lineages are DDAH1, IDH1, and BPNT1. Each is linked with GCC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GCC2-to-partner and partner-to-GCC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCC2 versus DDAH1 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCC2→partner) and Y-score (partner→GCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDAH1 →	+0.566	+0.479	<.001	<.001	3	5
UCEC	IDH1 →	+0.538	+0.398	.001	<.001	3	5
UCEC	BPNT1 →	+0.391	+0.455	.004	<.001	3	5
PDAC	YME1L1 →	-0.341	-0.344	<.001	<.001	3	4
BRCA	SLC2A1 →	-1.008	-0.781	<.001	<.001	3	4
OV	RPL12 →	-0.241	-0.732	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,989 associations by consensus.

GCC2 vs DDAH1 — BRCA

Explore this scatter interactively →