GCC2

Across TCGA patient cohorts, GCC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 33,071 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GCC2-associated proteins across cancer lineages are COG3, COG1, and COG2. Each is linked with GCC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both GCC2-to-partner and partner-to-GCC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCC2 versus COG3 in UCEC, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCC2→partner) and Y-score (partner→GCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COG3 →	+0.344	+0.345	<.001	<.001	3	10
BRCA	COG1 →	+0.354	+0.355	<.001	<.001	3	9
BRCA	COG2 →	+0.381	+0.349	<.001	<.001	3	9
BRCA	COG4 →	+0.319	+0.348	<.001	<.001	3	9
UCEC	TMF1 →	+0.383	+0.345	<.001	<.001	3	9
BRCA	PDXDC1 →	+0.601	+0.310	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 33,071 associations by consensus.

GCC2 vs COG3 — UCEC

Explore this scatter interactively →