GCC1

Across TCGA patient cohorts, GCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCC1-associated genes across cancer lineages are GSTK1, PLAGL1, and FXYD6. Each is linked with GCC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GCC1-to-partner and partner-to-GCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCC1 versus GSTK1 in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCC1→partner) and Y-score (partner→GCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GSTK1 →	+0.672	+0.167	<.001	<.001	3	5
UCEC	PLAGL1 →	-1.104	-0.140	<.001	.008	3	4
UCEC	FXYD6 →	-0.686	-0.139	<.001	<.001	3	4
BRCA	RAB19 →	+0.841	+0.204	<.001	<.001	3	4
UCEC	CYB5R1 →	+0.803	+0.164	.003	.001	3	4
GBM	PGAP4 →	-0.932	-0.149	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,814 associations by consensus.

GCC1 vs GSTK1 — UCEC

Explore this scatter interactively →