GCC1

Across TCGA cell cohorts, GCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,898 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GCC1-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Negative regulation of autophagy, and Endocytic recycling. Each is linked with GCC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both GCC1-to-partner and partner-to-GCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by GCC1-low versus GCC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCC1→partner) and Y-score (partner→GCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Vesicle-mediated transport to the plasma membrane →	+0.056	+0.771	.001	.001	3	14
KIDNEY	Negative regulation of autophagy →	+0.070	+0.745	.002	.002	3	13
SOFT_TISSUE	Endocytic recycling →	+0.072	+0.927	<.001	<.001	3	13
SKIN	Retrograde transport, endosome to Golgi →	+0.074	+0.798	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.065	+0.589	.002	.001	3	12
SOFT_TISSUE	Peptidyl-serine phosphorylation →	+0.087	+0.811	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,898 associations by consensus.

Vesicle-mediated transport to the plasma membrane by GCC1 expression — SOFT_TISSUE

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