GBX1

Across TCGA patient cohorts, GBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,705 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible GBX1-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Peptidyl-lysine modification, and Positive regulation of DNA repair. Each is linked with GBX1 in more than 22 cancer types. Because this analysis shows association rather than direction, both GBX1-to-partner and partner-to-GBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by GBX1-low versus GBX1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBX1→partner) and Y-score (partner→GBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of organelle assembly →	+0.065	+0.218	<.001	.001	3	23
STAD	Peptidyl-lysine modification →	+0.059	+0.152	<.001	<.001	3	22
STAD	Positive regulation of DNA repair →	+0.055	+0.158	<.001	<.001	3	22
STAD	Regulation of transcription by RNA polymerase I →	+0.071	+0.123	<.001	<.001	3	22
STAD	Regulation of microtubule polymerization →	+0.054	+0.150	<.001	<.001	3	21
STAD	Positive regulation of protein ubiquitination →	+0.081	+0.258	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,705 associations by consensus.

Positive regulation of organelle assembly by GBX1 expression — ESCA

Explore this box plot interactively →