GBX1

Across TCGA cell cohorts, GBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,189 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GBX1-associated GO terms across cancer lineages are Cell cycle G1/S phase transition, Regulation of termination of RNA polymerase II transcription, and Regulation of termination of DNA-templated transcription. Each is linked with GBX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GBX1-to-partner and partner-to-GBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle G1/S phase transition grouped by GBX1-low versus GBX1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GBX1→partner) and Y-score (partner→GBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cell cycle G1/S phase transition →	+0.075	+0.337	<.001	.004	3	6
SOFT_TISSUE	Regulation of termination of RNA polymerase II transcription →	+0.090	+0.346	<.001	.003	3	6
SOFT_TISSUE	Regulation of termination of DNA-templated transcription →	+0.090	+0.346	<.001	.003	3	6
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.151	+0.629	<.001	.003	3	5
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.062	+0.320	.001	.006	3	5
OVARY	Regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.092	+0.064	.002	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,189 associations by consensus.

Cell cycle G1/S phase transition by GBX1 expression — SOFT_TISSUE

Explore this box plot interactively →