GBP4

Across TCGA patient cohorts, GBP4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,646 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GBP4-associated genes across cancer lineages are APOBEC3H, ETV7, and GRAP2. Each is linked with GBP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both GBP4-to-partner and partner-to-GBP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GBP4 versus APOBEC3H in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP4→partner) and Y-score (partner→GBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOBEC3H →	+0.761	+0.641	<.001	<.001	3	10
BRCA	ETV7 →	+1.374	+0.762	<.001	<.001	3	10
HNSC	GRAP2 →	+1.003	+0.782	<.001	<.001	3	10
HNSC	IL2RB →	+1.303	+0.944	<.001	<.001	3	10
BRCA	GZMH →	+1.314	+0.664	<.001	<.001	3	10
HNSC	SLA2 →	+1.161	+0.891	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,646 associations by consensus.

GBP4 vs APOBEC3H — BRCA

Explore this scatter interactively →